STUDIES ON HEPATITIS B VACCINES

نویسندگان

  • H KALANTARI School of Pharmacy. Ahwaz University of Medical Sciences, Ahwaz, Islamic Republic of Iran.
  • ME MAKVANDI From the' Department of Microbiology and Immunology, Ahwaz University of Medical Sciences, Ahwaz,
  • PY DIGHE Beharat Serum and Vaccines, Thana, University of Bombay
چکیده مقاله:

HBs vaccines were prepared by three different methods: 1) Heat inactivation (Krugman, et.al 1971)2) Ammonium sulphate precipitation followed by column chromatography (Sephadex G-200) 3) PEG-6000 (polyethylene glycol) precipitation followed by column chromatography using Sephadex G-200. Their efficacy was studied in guinea pigs, and the results compared with commercial Japanese vaccine (Green Cross Corporation, Osaka, Japan). We conclude that vaccine prepared by PEG-6000 precipitation gives better results.

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عنوان ژورنال

دوره 4  شماره 2

صفحات  125- 128

تاریخ انتشار 1990-05

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